5 facts about The Ageing Revolution: How Nicotinamide Riboside (NR) Can Transform Your Life

Just when you thought everything had been invented, along comes Nicotinamide Riboside (NR) to revolutionise the science of ageing. This compound, an advanced form of vitamin B3, raises NAD+ levels in the body, an essential coenzyme for cellular energy production. By boosting NAD+, NR enhances mitochondrial function, optimising ATP production and improving cellular health. Clinical studies have shown that NR supplementation can significantly raise NAD+ levels, offering new hope in the fight against ageing and cellular fatigue.

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Scientific Studies Supporting the Efficacy of Nicotinamide Riboside

1. Study on Raising NAD+ Levels

A study published in Cell Metabolism showed that NR supplementation significantly raises NAD+ levels in the blood. In this clinical trial, participants who took NR showed a notable increase in their NAD+ levels, with no significant adverse effects.

2. Improved Mitochondrial Function and ATP Production

A clinical trial published in Nature Communications showed that NR improves mitochondrial function by increasing NAD+ levels. This increase optimises ATP production in human cells and animal models, thereby improving cellular health and energy efficiency.

3. DNA Repair and Cellular Protection

Research has found that NR supplementation improves cells' ability to repair damaged DNA. A study in Science showed that raising NAD+ levels through NR helps reduce the risk of mutations and improves genomic stability.

4. Reduced Cellular Fatigue and Improved Physical and Mental Endurance

A study published in Journal of Clinical Investigation showed that NR supplementation not only increases NAD+ levels but also improves physical and mental endurance. Participants experienced reduced fatigue and improved cognitive performance.

5. Synergy between NR and Magnesium in Mitochondrial Health

Research published in Aging Cell found that combining NR with magnesium bisglycinate significantly improves mitochondrial function and energy production. This study highlights how both supplements work together in synergy to optimise cellular health and combat fatigue.

and the most curious one, once you realise just how much it helps prevent ageing

Age-related hearing loss (ARHL) is the most common sensory disability affecting the elderly human population. It manifests as a progressive, bilateral decline in hearing function, starting with high-frequency sounds. One in three adults over 65 shows clinically diagnosable hearing loss, and the risk doubles with each decade of life (Briggs, 2019). Due to its slow progression, ARHL is often overlooked. However, it is widely associated with cognitive decline, social isolation and accident risk. Combined with the projected rise in the world's elderly population, ARHL poses an enormous public health challenge.

Here's the scientific article for you.

Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice - Okur - 2023 - Aging Cell - Wiley Online Library